The public discussion took place for the Doctoral student (Hassan Falah Lahej)  At Anbar University, College of Science, Department of Biology, for his tagged thesis

" Molecular typing of multidrug resistantt Klebsiella pneumonia using Multi-locus sequence type alleles and capsular type-specific" In the Sunday, 12/5/ 2024, at Ibn Sina Hall.

The discussion committee consisted of:

This study focuses on two main aims: To survey the most common capsular types in local isolates for first time in Anbar province/Iraq on the molecular level and to distinguish between these infectious pathogen strains by using Multilocus sequence typing (MLST) for more efficient epidemiological and surveillance analysis, in order to determine the source of these strains (invasive or purebred). Molecular typing result of 15 isolates which had send to sequencing and which their have been chosen as more resist toward antimicrobial agents show that three isolates were found to be a new strains that have never been identified before in all the world, , while the other strains demonstrated a preregistered with ST16, ST218 and ST283.

 For first time, three isolates registered as a new strains in the world with sequence strains ( ST6434, ST6727 and ST6769), with 3 alleles (320 for gapA, 360 and 361 for rpoB ) were identified for the first time. The study were found that the capsule K2 type had been a high frequency among MDR- K. pneumoniae isolated of Urinary tract infection with relation of the presence of the capsule with hyper-mucoviscous strains.

The results showed a statistically significant relationship between the present of capsule and string test at P-value (0.0324), and a statistically significant relationship between the present of capsule with strong biofilm formation at P-value (0.002). The results indicating that it is not enough to monitor antibiotic resistance alone but must also carefully monitor virulence determinants to ensure that highly resistant strains do not spread. On the other hand, it is not enough to monitor antibiotic resistance alone but must also carefully monitor virulence determinants to ensure that highly resistant strains do not spread.