The public discussion of the master’s student (Sarah Abdul Hameed Abdul Aziz) in the Department of Chemistry - College of Science - University of Anbar was held on Monday 7/11/2022 at Jaber Bin Hayyan Hall in the College of Science about her thesis tagged:

Green Synthesis of Iron and Cobalt Oxides Nanoparticles: Their Applications as Anti-cancer and Anti-pathogenic Bacteria

In this study, iron oxide (Fe2O3) and cobalt oxide (Co3O4) nanoparticles were successfully prepared by the green method from persimmon extract (Diospyros kaki). This study used to evaluate the efficiency of Fe2O3 NPs and Co3O4 NPs in vitro for the Hepatocellular carcinoma cancer cell line (Hep-G2) and the Colorectal cancer cell line (HT-29), as well as the effectiveness of these nanoparticles in suppressing the growth of Staphylococcus aureus and Escherichia coli.

 Hep-G2 and HT-29 cancer cell lines were exposed to prepared iron and cobalt oxide nanoparticle respectively for concentrations (125, 250, 500, and 750) μg/mL the inhibition rate of growth in cells was measured for 72 hours. The cytotoxicity screening showed that there was a highly toxic effect on the cancer cells inhibition increased with increasing concentration.

         Esandcherichia coli and Streptococcus pyogenes were exposed to a series of concentrations from prepared iron and cobalt oxides nanoparticles (62.5, 125, 250, and 500) μg/mL. The results exhibited significant inhibitory activity and the rate of bacterial growth inhibition increased with increasing concentration. From this study, it can be inferred that the preparation of Fe2O3 NPs and Co3O4 NPs yields promising early outcomes for work in the future as an anti-cancer and anti-microbial agent.