The public discussion of the master’s student (Shahd Mahmood Shaker), Department of Chemistry - College of Science - University of Anbar, took place on Wednesday 10/26/2022 at Jaber Bin Hayyan Hall in the College of Science about her thesis tagged:

Biosynthesis of Copper and Titanium Oxides Nanoparticles and Evaluation of their Biological Applications

This study was conducted in view of the importance of nanoparticles in many sectors, including medicine, This approach has been utilized to create nanoparticles with few side effect  and safe medicinal properties Copper oxide (CuO) and Titanium dioxide (TiO2)  NPs were effectively synthesized using a green technique from pears extract (pyrus comminus).  This study used to evaluate efficiency of CuO NPs and TiO2 NPs for Colorectal adenocarcinoma cancer cell lines (HT-29) and human Hepatocellular carcinoma (Liver cancer)  cell lines (Hep-G2) in vitro. as well as the effectiveness of these nanoparticles in suppressing the growth of Streptococcus pyogenes and Acinetobacter baumannii.

The results of the cytotoxicity testing indicated that there was a highly toxic effect on the cancer cells inhibition increased with increasing concentration. The anti-bacterial properties were also identified against streptococcus pyogenes (G+) and Acinetobacter baumannii (G-) by an agar well diffusion assay and MIC assay were exposed to a series of concentration for nanoparticles prepared. The results exhibited significant inhibitory activity and the rate of bacterial growth inhibition increased with increasing concentration. Biosynthesized nanoparticles have shown high efficiency as anticancer and antibacterial agents in a dose dependent manner.

Finally, our findings demonstrated that the green manufacture of CuO NPs and TiO2 NPs from pears extract produced promising preliminary results for future research that might be employed in anticancer and antimicrobial drugs.